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A possible mechanism to understand how Pycnogenol contributes to lower glucose blood levels could be that sugar absorption was slowed down in patients supplemented with Pycnogenol by inhibition of -glucosidase, the enzyme that disassembles starch ( In 21 men with moderate erectile dysfunction, supplementation with 120 mg Pycnogenol per day over a period of three months significantly decreased total cholesterol from 5.41 to 4.98 mmol/L and LDL-cholesterol from 3.44 to 2.78 mmol/L ( supplementation increased the antioxidant activity of plasma determined by the FRAP (ferric reducing ability of plasma) method significantly by 15%

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